A European road transport system that is 50% more efficient than today could be achieved, by 2030, by adopting the range of research and innovation priorities defined in this Strategic Research Agenda. This ambitious objective reflects ERTRAC's contribution to Europe's efforts to address the 'grand challenges of our time', and to bring sustainability to the European community (Lund, 2009). This contribution involves bringing significant improvements to the European road transport system. The research and innovation proposed in this SRA will enable such improvements by addressing the broad range of challenges related to the road transport system, including: the supply of energy and resources; global climate change and the environment; health and safety; and increased global competitiveness of the road transport industry leading to economic growth and high quality employment in Europe. The approach taken by the SRA recognizes, in particular, the societal demand for decarbonization, reliability and safety of the road transport system from a user's perspective, and establishes clear guiding objectives towards 2030 for each of the related indicators.